Projects Profile
Project Title
Development of software for monitoring blood flow to the brain
Partnership
Dr. David M. Simpson from University of Southampton
Dr. Jia Lu from Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Project Aim
The aim of this project is to test, compare and optimise various published methods of assessing blood flow to the brain and identify the most appropriate technique to include in commercial software.
Inspiration for the projects
Impaired control of blood flow in the brain has been linked to a number of serious neurological complications, including stroke and the consequences of head-trauma and premature birth of neonates. In order to assess the impairment of this control system, medical staff non-invasively monitor blood flow in the brain, using Doppler ultrasound for flow measurements. This project will develop software to analyse this data for the assessment of patient’s blood flow control
Innovation Elements
There is significant interest in the control of blood flow in the brain within medical and physiological research. To date no single method for assessing autoregulation has become accepted as a gold standard and the field has not yet achieved its clinical potential. The outcome of this project will be a set of clear recommendations, based on data analysis and testing of methods, on which method is the best suited for routine application in research and clinical practice. The best methods will then be optimized in preparation for implementation.
Commercial Potential and Further Development
This project has very strong commercial potential. A successful result may lead to development of a new software package to be bundled with equipment manufactured by the Chinese collaborating company (Delicate Electronics Co.Ltd) or sold separately for use with other equipment

